Two people were killed and two more injured when a small plane crashed in São Paulo, emergency services have confirmed.

The aircraft came down on the busy Marques de Sao Vicente Avenue, colliding with a bus on the ground.

A passenger on the bus and a motorcyclist hit by debris were taken to hospital, while those who died were aboard the plane, fire department spokesperson Captain Maycon Cristo said.

Smoke could be seen rising over Brazil’s largest city in the aftermath of the incident.